But witnesses said civilians were among about 50 people killed.
Several fighter planes took part in the raid and hit a civilian area by mistake, a local official in Abyan, a part of the former South Yemen republic authorities say has become a regrouping base for Islamist militants, told AFP.
Raids also took place in the capital Sanaa and the neighbouring district of Arhab, to the northeast, a defense ministry official.
Some of the strikes against suspected Al-Qaeda hideouts in Yemen this week were undertaken by local forces alone, US officials said.
The television network said one of the targeted sites was a suspected training camp for Al-Qaeda north of Sanaa while the second was at a site where "an imminent attack against a US asset was being planned,'' according to officials.
It identified raids carried out by Yemeni security forces at three separate location in addition to the two US cruise missile attacks.